Self-Amplifying mRNA (saRNA) Vaccine for Nipah Virus

Gennova Biopharmaceuticals is developing an innovative self-amplifying mRNA (saRNA) vaccine candidate targeting the Nipah virus. This initiative is supported by expanded funding from the Coalition for Epidemic Preparedness Innovations (CEPI).

About the Nipah Virus:

1. A zoonotic virus from the Paramyxovirus family.
2. Fruit bats serve as its natural reservoir.

Understanding saRNA Vaccines:

1. Unlike traditional vaccines that introduce antigens directly, mRNA vaccines instruct the body to produce antigenic proteins.
2. Self-amplifying mRNA (saRNA) vaccines go a step further by enabling the body to replicate mRNA, generating the required antigen in greater quantities.
3. This approach enhances the immune response while requiring lower doses compared to conventional mRNA vaccines.

 

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